Pharmacological approaches are of weak efficacy in fibromyalgia and should be combined with nonpharmacological therapies, for a synergistic effect, tailored to each patient. Keywords: Fibromyalgia, Pharmacological treatments, Drugs, Opioids Abstract Pharmacological approaches are frequently proposed in fibromyalgia, based on different rationale. Some treatments are proposed to alleviate symptoms, mainly pain, fatigue, and sleep disorder. Other treatments are proposed according to pathophysiological mechanisms, especially central sensitization and abnormal pain modulation. Globally, pharmacological approaches are weakly effective but market authorization differs between Europe and United States. Food and Drug Administration–approved medications for fibromyalgia…
Read MoreFibromyalgia: do I tackle you with pharmacological treatments?
