Tryptophan Pathway May Control Anxiety Levels in Women with Fibromyalgia,

Fibromyalgia patients’ anxiety symptoms vary according to the pathway-specific metabolism of tryptophan, a precursor to the “happy hormone” serotonin, a small study suggests. Lower levels of tryptophan also were associated with increased pain intensity in people with muscle pain from temporomandibular Tryptophan Pathway May Control Anxiety Levels in Women with Fibromyalgia, Study Suggestsdisorders affecting the movement of the jaw, the researchers found. Titled “Plasma tryptophan and kynurenine in females with temporomandibular disorders and fibromyalgia—An exploratory pilot study,” the study was published in the Journal of Oral Rehabilitation. Chronic pain can manifest itself as a widespread or localized phenomenon. Fibromyalgia (FM) is a chronic condition that’s characterized by widespread pain, fatigue, and disturbed sleep, ultimately leading to poor quality of life. Despite sharing some of fibromyalgia’s features, temporomandibular disorders myalgia (TMDM) are defined by pain localized to the chewing muscles. Anxiety and depression symptoms are commonly found in both chronic pain diseases. Evidence indicates TMDM and FM are associated with changes in serotonin metabolism. Tryptophan (TRP) is an essential amino acid and serotonin’s precursor, whose main metabolic route is the

Reference:https://fibromyalgianewstoday.com/2020/01/03/tryptophan-pathway-may-control-anxiety-levels-women-fibromyalgia/

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